Excavations in the Sanctuary of Ismenion Apollo in Thebes revealed a later cemetery of Early and Middle Byzantine burials. Analysis of these burials has generated new information about burial practices in the transition from late Antique to Christian Thebes. A pathological survey of the skeletons has found that a remarkably high percentage of individuals suffered from significant, pathologies, including cancers, brucellosis, extensive trauma, and leprosy. The very high percentage of individuals with leprosy suggests there may have been a nearby leprosarium or hospital, and that this cemetery served to bury those who died of particularly debilitating or disfiguring diseases.