DAY 1 - THURSDAY 17 OCTOBER

• 09:00-10:00 Registration
• 10:00-10:30 Opening Remarks
• 10:30-12:00 Oral Session 1 | Immunology, Chair: Dr. Konstantinos Lazaridis, Dr. Vasiliki Kyrargyri
• 10:30-10:45 Anastasia Dagkonaki, Hellenic Pasteur Institute, «Maturation of circulating Ly6ChiCCR2+ monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis»
• 10:45-11:00 Eleni Konstantina Loxa, Hellenic Pasteur Institute, «Application of a competitive ELISA utilizing trimeric spike protein for the detection of neutralizing antibodies in sera of vaccinated individuals against SARS-CoV-2 and patients infected with SARS-CoV-2 variant strain Omicron»
• 11:00-11:15 Stavros Naoum, Hellenic Pasteur Institute, «Tissue factor-expressing neutrophil extracellular traps formation in primary antiphospholipid syndrome is driven by antiphospholipid antibody-mediated platelet activation, subsequent platelet-neutrophil interaction and autophagy induction»
• 11:15-11:30 Eleni Ntoukaki, Hellenic Pasteur Institute, «Investigation of the mechanism of action of an antigen-specific therapy for myasthenia gravis and strategies for pharmacokinetic optimization»
• 11:30-11:45 Eleni Papagianni, University of Ioannina, «The role of neutrophil extracellular traps in the pathogenesis of RA-ILD; the effect of the anti-fibrotic agent Nintedanib in the inflammatory responses of the disease»
• 11:45-12:00 Aristotelis Petris, Hellenic Pasteur Institute, «Neutrophil extracellular trap (NETs) release in Helicobacter pylori infection»
• 12:00-12:15 Biotechnological Companies Session: P Zafeiropoulos, «Novel cellbased
• Applications in Research and Therapeutics»
• 12:15-14:00 Poster Session 1 + Lunch Break
• 14:00-16:15 Oral Session 2 | Bioinformatics, Chair: Dr. Artemis G Hatzigeorgiou
• 14:00-14:15 Dimitrios Christos Tremoulis, Hellenic Pasteur Institute, «A scalable bioinformatics platform for the streamlined analysis of single cell RNA-seq data»
• 14:15-14:30 Despoina Kiouri, National Hellenic Research Foundation & National and Kapodistrian University of Athens, «Deep Neural Network Framework for Predicting Protein-Protein Interactions from Structural Data»
• 14:30-14:45 Agoritsa Kalampaliki, BSRC Alexander Fleming, «A Root Mean Square Deviation Estimation Algorithm (REA) and its use for improved RNA Structure Prediction»
• 14:45-15:00 Dimitra Panou, BSRC Alexander Fleming, National and Kapodistrian University of Athens, «Biomedical Question Answering using a ’Farm’ of Open Large Language Models»
• 15:00-15:15 Faidon Zacharias Brotzakis, BSRC Alexander Fleming and University of Cambridge, «Computational design of antibodies against disease relevant molecular targets»
• 15:15-16:15 Keynote 1 | Dr. Emmanouil Maragkakis «The genomics of aging: translating large - scale data to molecular mechanisms»
• 16:15-16:30 Coffee Break
• 16:30-18:00 Oral Session 3 | Microbiology, Chair: Dr. Haralabia Boleti, Dr. Niki Vassilaki
• 16:30-16:45 Marianna Arvaniti, Agricultural University of Athens, «Dormancy induction and outgrowth heterogeneity of Listeria monocytogenes is affected by stress history and type of growth»
• 16:45-17:00 Antonia Efstathiou, Hellenic Pasteur Institute, «Exosomes as a vaccine candidate against visceral leishmaniasis»
• 17:00-17:15 Nikolaos Moustakas, Hellenic Pasteur Institute, «Qualitative and quantitative detection of Non Helicobacter pylori Helicobacter (NHPΗ) species in human gastric biopsies»
• 17:15-17:30 Eleni Paximadi, «Human Endogenous Retro Viruses (HERVs) and Multiple Sclerosis»
• 17:30-17:45 Dimitra Toubanaki, Hellenic Pasteur Institute, «Utilizing powerful molecular tools to understand environment-threatening viruses: the case of viral encephalopathy»
• 17:45-18:00 Vasileios Gouzouasis, Hellenic Pasteur Institute, «COVID-19 Infection Reactivates Epstein-Barr Virus and Precipitates the First Clinical Episode in a Greek Cohort of Multiple Sclerosis Patients»
• 18:00-19:00 Keynote 2 | Dr. Evangelos Giamarellos «Personalized infection treatment»
• 19:00-21:00 Official presentation of the 100th Anniversary Edition Pasteur Album
• 21:00 Cheese & Wine

DAY 2 - FRIDAY 18 OCTOBER

• 09:30-10:45 Oral Session 4 | Bioinformatics, Chair: Dr. Timokratis Karamitros, Dr. Magdalini Bletsa
• 09:30-09:45 Marina Petsana, University of Thesally and Hellenic Pasteur Institute, «In Silico Identification and Analysis of Proteins Containing the Phox Homology Phosphoinositide-Binding Domain in Kinetoplastea Protists»
• 09:45-10:00 Anargyros Skoulakis, University of Thesally and Hellenic Pasteur Institute, «Machine Learning-Based Prediction of Antimicrobial Resistance in ESCAPEE Pathogens Using Genomic Data»
• 10:00-10:15 Maria Bousali, Hellenic Pasteur Institute, «HBV Integrations: How Does Viral Load Affect Their Frequency and Genomic Distribution?»
• 10:15-10:30 Alexandros Galaras, BSRC Alexander Fleming and University of Thesally, «LncRNA EPB41L4A-AS1 encodes a novel mitochondrial microprotein with tumor suppressive effects»
• 10:30-10:45 Chrysoula Kaligerou, Hellenic Pasteur Institute, «Development of an analytical NGS workflow for the clinical interpretation of whole exome sequencing data from patients with Multiple Myeloma»
• 10:45-11:00 Coffee Break
• 11:00-12:15 Oral Session 5 |Structural Biology – Biotechnology & Public Health, Chair: Dr. Emmanouil Angelakis, Dr. Marios Zouridakis
• 11:00-11:15 Oleksii Kupreienko, Hellenic Pasteur Institute and Agricultural University of Athens, «Towards the development of novel allosteric activators for human angiotensin-converting enzyme 2»
• 11:15-11:30 Maria-Evgenia Politi, Hellenic Pasteur Institute and Agricultural University of Athens, «Expression, purification and characterization of human tyrosinase and crystallographic studies of a bacterial structural surrogate»
• 11:30-11:45 Maria Voumvouraki, National and Kapodistrian University of Athens, «Comparing different lysis conditions for proteomics analysis of amyloid deposits in biopsies for diagnostics»
• 11:45-12:00 Constatinos Karamalis, University of West Attica, «Development of a molecular assay for the identification of Streptococcus spp. directly in clinical samples and the impact on an accurate diagnosis in public health measures»
• 12:00-12:15 Eirini Kosta, Hellenic Pasteur Institute & University of West Attica, «Subtyping of L. infantum strains from Greece by using genomic DNA isolated from cultivated parasites and different PCR-based techniques»
• 12:15-12:30 Biotechnological Companies Session: Antisel, “Witness the Next- Generation of Multiomics”
• 12:30-14:00 Poster Session 2 + Lunch Break
• 14:00-15:00 Scientific Image Session & Neuroholics
• 15:00-15:30 Coffee Break
• 15:30-16:30 Keystone 3 | Dr. Mark Mattson «Understanding and Counteracting Brain Aging»
• 16:30-18:00 Oral Session 6 | Neurobiology, Chair: Dr. Dimitra Thomaidou, Dr. Florentia Papastefanaki
• 16:30-16:45 Elissavet Akrioti, Hellenic Pasteur Institute, «Deciphering and targeting early synaptic dysfunction in pre-clinical models of familial Parkinson’s disease»
• 16:45-17:00 Spyridon Antoniadis, Aristotle University of Thessaloniki and National and Kapodistrian University of Athens, «Connecting Connectomes to Physiology via optogenetics and complex network theory: an ex vivo Investigation of Spontaneous Oscillations in the Mouse Motor Cortex»
• 17:00-17:15 Olympia Apokotou, Hellenic Pasteur Institute, «Control iPSC-derived astrocytes rescue P.A53T-αSyn patient-iPSC-derived neurons from Parkinson’s disease-related pathology»
• 17:15-17:30 Maria Margariti, Hellenic Pasteur Institute, «In vivo study of the effect of microglial BIN1 deletion on mouse brain under homeostatic and neuroinflammatory conditions»
• 17:30-17:45 Myrto Patagia Bakaraki, University of West Attica, «The Impact of Multisensory Strategies on Functionality in Adults with Neurological Disorders»
• 17:45-18:00 Athena Boutou, Hellenic Pasteur Institute, «Microglia regulate cortical remyelination via ΤNFR1-dependent phenotypic polarization»
• 18:00-19:00 Keystone 4 | Dr. George Paxinos «Is the brain in the Goldilocks Zone?»
• 19:00-20:00 Award Ceremony | Closing Remarks
• 20:00 Latin Garden Party & Dinner